Thursday, June 28, 2007

Recognition of Depression in Aphasic Stroke Patients

A.C. Laskaa, B. Mårtenssonc, T. Kahanb, M. von Arbina, V. Murraya

Department of Clinical Sciences, Karolinska Institutet, Danderyd Hospital,
aDivision of Internal Medicine,
bDivision of Cardiology, and
cDepartment of Clinical Neuroscience, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden

Address of Corresponding Author

Cerebrovascular Diseases 2007;24:74-79 (DOI: 10.1159/000103119)

goto top of page Key Words

  • Aphasia, depression
  • Acute stroke
  • Validity, assessment of depression

goto top of page Abstract

Background: Data on post-stroke depression in aphasia are scarce. Methods: Eighty-nine acute stroke patients with aphasia of all types were followed for 6 months to investigate if depression can be reliably diagnosed (DSM-IV criteria) and validly assessed by the verbal Montgomery-Åsberg Depression Rating Scale (MADRS) and a global technique (Clinical Global Impressions Rating Scale for Severity). A standard aphasia test was performed. Results: In 60 patients (67%) at baseline and in 100% at 6 months, comprehension allowed a reliable DSM-IV diagnosis. Among these patients MADRS was feasible in 95% at baseline and in 100% at 6 months. The assistance of relatives and staff increases the feasibility and decreases the validity. Depression was identified in 24% during the 6 months. Conclusion: Depression diagnosis and severity rating can reliably be made in the acute phase in at least two thirds of aphasic patients, and feasibility increases over time.

Copyright © 2007 S. Karger AG, Basel

goto top of page Author Contacts

Ann Charlotte Laska, MD
Department of Clinical Sciences, Karolinska Institutet, Danderyd Hospital
Division of Internal Medicine
SE-182 88 Stockholm (Sweden)
Tel. +46 8 655 6409, Fax +46 8 622 6810, E-Mail

goto top of page Article Information

Received: August 22, 2006
Accepted: January 3, 2007
Published online: May 23, 2007
Number of Print Pages : 6
Number of Figures : 1, Number of Tables : 3, Number of References : 23


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